Invention Grant
US07671075B2 Substituted phenylsulfonamide inhibitors of beta amyloid production
失效
β-淀粉样蛋白生成的取代苯磺酰胺抑制剂
- Patent Title: Substituted phenylsulfonamide inhibitors of beta amyloid production
- Patent Title (中): β-淀粉样蛋白生成的取代苯磺酰胺抑制剂
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Application No.: US11528001Application Date: 2006-09-27
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Publication No.: US07671075B2Publication Date: 2010-03-02
- Inventor: Anthony Frank Kreft , Derek Cecil Cole , Kevin Roger Woller , Joseph Raymond Stock , Kristina Martha Kutterer , Dennis Martin Kubrak , Charles William Mann , William Jay Moore , David Scott Casebier
- Applicant: Anthony Frank Kreft , Derek Cecil Cole , Kevin Roger Woller , Joseph Raymond Stock , Kristina Martha Kutterer , Dennis Martin Kubrak , Charles William Mann , William Jay Moore , David Scott Casebier
- Applicant Address: US NJ Madison US MA Woburn
- Assignee: Wyeth,ArQule, Inc.
- Current Assignee: Wyeth,ArQule, Inc.
- Current Assignee Address: US NJ Madison US MA Woburn
- Agency: Howson & Howson LLP
- Agent Scott K. Larsen
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/34 ; A61K31/357 ; A61K31/4245 ; C07C311/17 ; C07D209/14 ; C07D271/12 ; C07D307/52 ; C07D317/08
Abstract:
Compounds of Formula I, wherein R1-R8 are defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs thereof. Uses of these compounds for inhibiting beta amyloid production and for the prevention and treatment of Alzheimer's Disease and Down's syndrome are also described.
Public/Granted literature
- US20070037778A1 Substituted phenylsulfonamide inhibitors of beta amyloid production Public/Granted day:2007-02-15
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