Invention Grant
US07671078B2 Isothiourea derivatives of imadazo[2,1-b]Thiazoles and 5,6-dihydro derivatives thereof useful as CXCR4 chemokine receptor inhibitors
失效
咪唑并〔2,1-b〕噻唑及其5,6-二氢衍生物作为CXCR4趋化因子受体抑制剂有用的异硫脲衍生物
![Isothiourea derivatives of imadazo[2,1-b]Thiazoles and 5,6-dihydro derivatives thereof useful as CXCR4 chemokine receptor inhibitors](/docs/US/2010-03-02/US07671078B2/abs.jpg.600x600.jpg)
- Patent Title: Isothiourea derivatives of imadazo[2,1-b]Thiazoles and 5,6-dihydro derivatives thereof useful as CXCR4 chemokine receptor inhibitors
- Patent Title (中): 咪唑并〔2,1-b〕噻唑及其5,6-二氢衍生物作为CXCR4趋化因子受体抑制剂有用的异硫脲衍生物
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Application No.: US10590399Application Date: 2005-02-25
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Publication No.: US07671078B2Publication Date: 2010-03-02
- Inventor: Fraser Glickman , Markus Streiff , Gebhard Thoma , Hans-Günter Zerwes
- Applicant: Fraser Glickman , Markus Streiff , Gebhard Thoma , Hans-Günter Zerwes
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Hoxie & Associates LLC
- Priority: GB0404434.3 20040227
- International Application: PCT/EP2005/002014 WO 20050225
- International Announcement: WO2005/085219 WO 20050915
- Main IPC: C07D513/04
- IPC: C07D513/04 ; A61K31/429 ; C07D513/14 ; A61K31/519 ; A61P35/04 ; A61P37/06 ; A61P31/14
![Isothiourea derivatives of imadazo[2,1-b]Thiazoles and 5,6-dihydro derivatives thereof useful as CXCR4 chemokine receptor inhibitors](/abs-image/US/2010/03/02/US07671078B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to isothiourea derivatives of formula I: wherein R1 is a residue of one of the following structures: where the variables are as defined in the claims of the invention, as well as processes for production of these compounds.
Public/Granted literature
- US20070161618A1 Isothiourea derivatives Public/Granted day:2007-07-12
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