Invention Grant
US07671181B2 Polynucleotides encoding coccidian parasite casein kinase I, a chemotherapeutic target for antiprotozoal agents
失效
编码球虫寄生虫酪蛋白激酶I的多核苷酸，一种抗原虫药的化疗靶
- Patent Title: Polynucleotides encoding coccidian parasite casein kinase I, a chemotherapeutic target for antiprotozoal agents
- Patent Title (中): 编码球虫寄生虫酪蛋白激酶I的多核苷酸，一种抗原虫药的化疗靶
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Application No.: US10586374Application Date: 2005-01-12
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Publication No.: US07671181B2Publication Date: 2010-03-02
- Inventor: Robert G. K. Donald , Paul Liberator , Xiaotian Zhong
- Applicant: Robert G. K. Donald , Paul Liberator , Xiaotian Zhong
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Laura M. Ginkel; Sheldon O. Heber
- International Application: PCT/US2005/000955 WO 20050112
- International Announcement: WO2005/070180 WO 20050804
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; C12N1/20 ; C12P21/00
Abstract:
Isolated nucleic acid molecules encoding coccidian casein kinase I, CKI, enzymes from the species Eimeria tenella and Toxoplasma gondii are disclosed. The isolation of these coccidian CKI cDNA sequences results in the disclosure of purified forms of E. tenella and T. gondii CKI proteins, recombinant vectors and recombinant hosts which express coccidian CKI.
Public/Granted literature
- US20080280313A1 Coccidian Parasite Casein Kinase I as a Chemotherapeutic Target for Antiprotozoal Agents Public/Granted day:2008-11-13
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