Invention Grant
US07671182B2 Gene variants of signal transducer and activator of transcription-6 (STAT 6) variants and process of detection the same
有权
信号转导基因变体和转录因子6（STAT 6）变体的激活因子与检测过程相同
- Patent Title: Gene variants of signal transducer and activator of transcription-6 (STAT 6) variants and process of detection the same
- Patent Title (中): 信号转导基因变体和转录因子6（STAT 6）变体的激活因子与检测过程相同
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Application No.: US10814002Application Date: 2004-03-30
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Publication No.: US07671182B2Publication Date: 2010-03-02
- Inventor: Balram Ghosh , Rana Nagarkatti , Chandrika B. Rao
- Applicant: Balram Ghosh , Rana Nagarkatti , Chandrika B. Rao
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Abelman, Frayne & Schwab
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/04
Abstract:
The present invention relates to allelic variants of the human Signal Transducer and Activator of Transcription-6 (STAT6) gene and provides primers and methods suitable for the detection of these allelic variants for applications such as molecular diagnosis, prediction of an individual's disease susceptibility, and /or the genetic analysis of the STAT6 gene in a population. Specifically, the invention provides a method for detection of predisposition to atopic disorders/other immunological disorders such as, autoimmune disorders, inflammatory disorders, fibrosis, etc. where STAT6 plays an important role by screening for human Signal Transducer and Activator of Transcription-6 (STAT 6) gene variants.
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