Invention Grant
US07671251B2 In vivo assay for neurite outgrowth in zebrafish and its application in drug screening
有权
斑马鱼神经突生长的体内测定及其在药物筛选中的应用
- Patent Title: In vivo assay for neurite outgrowth in zebrafish and its application in drug screening
- Patent Title (中): 斑马鱼神经突生长的体内测定及其在药物筛选中的应用
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Application No.: US11327263Application Date: 2006-01-06
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Publication No.: US07671251B2Publication Date: 2010-03-02
- Inventor: Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
- Applicant: Chih-Ming Chou , I-Ching Lu , Gen-Der Chen , Chioh-Yueh Chen , Chang-Jen Huang
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Intellectual Property Connections, Inc.
- Agent Hsiu-Ming Saunders
- Main IPC: A01K67/027
- IPC: A01K67/027 ; G01N33/00
Abstract:
A genetically modified zebrafish embryo, comprising a HBNF cDNA or a NGF cDNA or a GDNF cDNA together with a cDNA encoding green fluorescent protein (GFP) so as to induce neurite outgrowth during said zebrafish embryonic development, and a method of using such genetically modified zebrafish embryo to identify a therapeutic agent are disclosed.
Public/Granted literature
- US20060179506A1 In vivo assay for neurite outgrowth in zebrafish and its application in drug screening Public/Granted day:2006-08-10
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