Invention Grant
- Patent Title: Compositions and methods for restoring sensitivity to treatment with HER2 antagonists
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Application No.: US10902374Application Date: 2004-07-30
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Publication No.: US07674460B2Publication Date: 2010-03-09
- Inventor: Ginette Serrero
- Applicant: Ginette Serrero
- Applicant Address: US MD Columbia
- Assignee: A&G Pharmaceutical, Inc.
- Current Assignee: A&G Pharmaceutical, Inc.
- Current Assignee Address: US MD Columbia
- Agency: Womble Carlyle Sandridge & Rice, PLLC
- Main IPC: A61K39/395
- IPC: A61K39/395

Abstract:
Methods and compositions for restoring growth inhibition sensitivity to a tumor cell resistant to growth inhibition by HER2 antagonists. The methods involve administering a PCDGF antagonist to the cell in an amount effective to stimulate or restore growth inhibition sensitivity to HER2 antagonists. The invention also provides treatment regimens, and therapeutic compositions comprising an HER2 antagonist and a PCDGF antagonist.
Public/Granted literature
- US20050106150A1 Compositions and methods for restoring sensitivity to treatment with HER2 antagonists Public/Granted day:2005-05-19
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