Invention Grant
- Patent Title: Treatment of cancer using HSV mutant
- Patent Title (中): 使用HSV突变体治疗癌症
-
Application No.: US11152591Application Date: 2005-06-13
-
Publication No.: US07674468B2Publication Date: 2010-03-09
- Inventor: Alasdair Roderick MacLean , Susanne Moira Brown , Nigel William Fraser , Bruce Paul Randazzo
- Applicant: Alasdair Roderick MacLean , Susanne Moira Brown , Nigel William Fraser , Bruce Paul Randazzo
- Applicant Address: GB Glasgow, Scotland US PA Philadelphia
- Assignee: Crusade Laboratories Limited,The Wistar Institute
- Current Assignee: Crusade Laboratories Limited,The Wistar Institute
- Current Assignee Address: GB Glasgow, Scotland US PA Philadelphia
- Agency: Swanson & Bratschun, LLC
- Priority: GB9415320.2 19940729
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/245
Abstract:
Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the γ34.5 gene in the long repeat region (RL) such that the γ34.5 gene is a non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
Public/Granted literature
- US20050260169A1 Treatment of cancer using HSV mutant Public/Granted day:2005-11-24
Information query
