Invention Grant
US07674586B2 Methods of identifying modulators of L-glutamate-gated chloride channel proteins from Rhipicephalus sanguineus
有权
鉴定来自R us属的L-谷氨酸盐化氯化物通道蛋白的调节剂的方法
- Patent Title: Methods of identifying modulators of L-glutamate-gated chloride channel proteins from Rhipicephalus sanguineus
- Patent Title (中): 鉴定来自R us属的L-谷氨酸盐化氯化物通道蛋白的调节剂的方法
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Application No.: US11620390Application Date: 2007-01-05
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Publication No.: US07674586B2Publication Date: 2010-03-09
- Inventor: Jeffrey W. Warmke , Youfeng Yang , Doris F. Cully , Michel J. Hamelin
- Applicant: Jeffrey W. Warmke , Youfeng Yang , Doris F. Cully , Michel J. Hamelin
- Applicant Address: US GA Duluth
- Assignee: Merial Limited
- Current Assignee: Merial Limited
- Current Assignee Address: US GA Duluth
- Agency: Merial Limited
- Agent Judy Jarecki-Black; Thomas Kowalski
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/00
Abstract:
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Rhipicephalus sanguineus glutamate gated chloride channels. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding R. sanguineus glutamate gated chloride channels, substantially purified forms of associated R. sanguineus glutamate gated chloride channels and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associated Rhipicephalus sanguineus glutamate gated chloride channels, which will be useful as insecticides.
Public/Granted literature
- US20080286770A1 DNA Molecules Encoding L-Glutamate-Gated Chloride Channels From Rhipicephalus Sanguineus Public/Granted day:2008-11-20
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