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US07674590B2 Methods for diagnosing and for monitoring the treatment of recurrent spontaneous abortion 有权
诊断和监测复发性自然流产的治疗方法

Methods for diagnosing and for monitoring the treatment of recurrent spontaneous abortion
Abstract:
The present invention discloses a method of diagnosis of immunological recurrent spontaneous abortion. The level of antinuclear antibody in a body fluid of a patient is determined and determined level is compared to the level of corresponding antinuclear antibody of a control. Particularly, isolated chromosome No. 2 or fragment thereof including fibronectin encoding gene derived from male(s) is used as antigen in the method of the present invention for determining the level of corresponding antinuclear antibody in a body fluid sample of the patient. The present invention also discloses a diagnostic kit for immunological recurrent spontaneous abortion, and method and kits for monitoring the therapeutic effect for immunological recurrent spontaneous abortion.
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