Invention Grant
US07674794B2 Fused bicycloheterocycle substituted quinuclidine derivatives 有权
稠合双环杂环取代的奎宁环衍生物

  • Patent Title: Fused bicycloheterocycle substituted quinuclidine derivatives
  • Patent Title (中): 稠合双环杂环取代的奎宁环衍生物
  • Application No.: US11599651
    Application Date: 2006-11-15
  • Publication No.: US07674794B2
    Publication Date: 2010-03-09
  • Inventor: Jianguo JiTao Li
  • Applicant: Jianguo JiTao Li
  • Applicant Address: US IL Abbott Park
  • Assignee: Abbott Laboratories
  • Current Assignee: Abbott Laboratories
  • Current Assignee Address: US IL Abbott Park
  • Agent Portia Chen
  • Main IPC: A61K31/4375
  • IPC: A61K31/4375 A61K31/55
Fused bicycloheterocycle substituted quinuclidine derivatives
Abstract:
Compounds of formula (I) wherein n is 0, 1, or 2; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
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