Invention Grant
- Patent Title: Thiazolypiperidine derivatives as MTP inhibitors
- Patent Title (中): 噻唑基哌啶衍生物作为MTP抑制剂
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Application No.: US10561989Application Date: 2004-06-02
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Publication No.: US07674803B2Publication Date: 2010-03-09
- Inventor: Philippe Guèdat , Francois Collonges , Hervé Dumas , Jean-Yves Ortholand , Jacques Decerprit , Jaxques Barbanton , Robert J. Foster , Peter Kane , Bernd Went
- Applicant: Philippe Guèdat , Francois Collonges , Hervé Dumas , Jean-Yves Ortholand , Jacques Decerprit , Jaxques Barbanton , Robert J. Foster , Peter Kane , Bernd Went
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: FR0307670 20030625
- International Application: PCT/EP2004/005931 WO 20040602
- International Announcement: WO2005/003128 WO 20050113
- Main IPC: A61K31/454
- IPC: A61K31/454 ; A61K31/4545 ; C07D417/14
Abstract:
The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2′, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
Public/Granted literature
- US20070054939A1 Thiazolypiperidine derivatives as mtp inhibitors Public/Granted day:2007-03-08
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