Invention Grant
US07674810B2 1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase
失效
1,1-二氧代-1H-1,10-苯并[d]异噻唑-3-基）-4-羟基-1,5-二氢 - 吡咯-2-酮抑制剂
![1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase](/docs/US/2010-03-09/US07674810B2/abs.jpg.600x600.jpg)
- Patent Title: 1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase
- Patent Title (中): 1,1-二氧代-1H-1,10-苯并[d]异噻唑-3-基）-4-羟基-1,5-二氢 - 吡咯-2-酮抑制剂
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Application No.: US11413872Application Date: 2006-04-28
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Publication No.: US07674810B2Publication Date: 2010-03-09
- Inventor: James F. Blake , Jay Bradford Fell , John P. Fischer , Robert Than Hendricks , Stacey Renee Spencer , Peter J. Stengel
- Applicant: James F. Blake , Jay Bradford Fell , John P. Fischer , Robert Than Hendricks , Stacey Renee Spencer , Peter J. Stengel
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLC
- Current Assignee: Roche Palo Alto LLC
- Current Assignee Address: US CA Palo Alto
- Agent Brian L. Buckwalter
- Main IPC: A01N43/80
- IPC: A01N43/80
![1,1-dioxo-1H-1Λ6-benzo[d]isothiazol-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one inhibitors of HCV polymerase](/abs-image/US/2010/03/09/US07674810B2/abs.jpg.150x150.jpg)
Abstract:
Compounds having the formula i wherein m, R1, R2, R4 and X1 are herein defined are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for inhibiting hepatitis replication, processes for making the compounds and synthetic intermediates used in the process.
Public/Granted literature
- US20060252785A1 Heterocyclic antiviral compounds Public/Granted day:2006-11-09
Information query
IPC分类:
