Invention Grant
US07674821B2 N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine [amide, sulfonamide, carbamate and urea) derivatives as cannabinoid CB1 receptor antagonists
失效
N - [（4,5-二苯基-3-烷基-2-噻吩基）甲基]胺[酰胺，磺酰胺，氨基甲酸酯和尿素）衍生物作为大麻素CB1受体拮抗剂
![N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine [amide, sulfonamide, carbamate and urea) derivatives as cannabinoid CB1 receptor antagonists](/docs/US/2010-03-09/US07674821B2/abs.jpg.600x600.jpg)
- Patent Title: N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine [amide, sulfonamide, carbamate and urea) derivatives as cannabinoid CB1 receptor antagonists
- Patent Title (中): N - [（4,5-二苯基-3-烷基-2-噻吩基）甲基]胺[酰胺，磺酰胺，氨基甲酸酯和尿素）衍生物作为大麻素CB1受体拮抗剂
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Application No.: US11764378Application Date: 2007-06-18
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Publication No.: US07674821B2Publication Date: 2010-03-09
- Inventor: Francis Barth , Christian Congy , Jean-Phillipe Ducoux , Murielle Rinaldi-Carmona
- Applicant: Francis Barth , Christian Congy , Jean-Phillipe Ducoux , Murielle Rinaldi-Carmona
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agent Balaram Gupta
- Priority: FR0413898 20041223
- Main IPC: A61K31/381
- IPC: A61K31/381 ; C07D333/22
![N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine [amide, sulfonamide, carbamate and urea) derivatives as cannabinoid CB1 receptor antagonists](/abs-image/US/2010/03/09/US07674821B2/abs.jpg.150x150.jpg)
Abstract:
The invention concerns compounds of formula (I), wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also concerns a method for preparing said compounds and their use as cannabinoid CB1 receptor antagonists.
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