Invention Grant
- Patent Title: Tetracyclic immunomodulatory compounds
- Patent Title (中): 四环免疫调节化合物
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Application No.: US10537538Application Date: 2003-12-12
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Publication No.: US07674906B2Publication Date: 2010-03-09
- Inventor: Ian Richard Matthews , Philip Huxley , Filippo Magaraci , Chris James Brennan , Muhammed Kamal Uddin , Lars Olof Göran Pettersson , Dorthe da Graca Thrige
- Applicant: Ian Richard Matthews , Philip Huxley , Filippo Magaraci , Chris James Brennan , Muhammed Kamal Uddin , Lars Olof Göran Pettersson , Dorthe da Graca Thrige
- Applicant Address: SE Lund
- Assignee: Active Biotech AB
- Current Assignee: Active Biotech AB
- Current Assignee Address: SE Lund
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: SE0203722 20021216
- International Application: PCT/SE03/01941 WO 20031212
- International Announcement: WO2004/055014 WO 20040701
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437
Abstract:
The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly, the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.
Public/Granted literature
- US20060035919A1 Tetracylic immunomodulatory compounds Public/Granted day:2006-02-16
Information query
