Low-leakage level-shifters with reduced leakage are disclosed. In one example, a level-shifter circuit to reduce leakage when there is an invalid supply voltage is described, including a level-shifter configured to shift a voltage of an digital input signal based on a first supply voltage to a digital output signal based on a second supply voltage, comprising a first transistor and a second transistor configured to set the digital output signal based on the digital input signal, a supply detector configured to generate a detection signal based on the first supply voltage, a disabler configured to, based on the detection signal, set the digital output signal of the level-shifter to a predetermined state, and a leakage reducer configured to, based on the detection signal, electrically disconnect the first and second transistors from the level-shifter.