A method for data transfer between two semi-synchronous clock domains in a System on Chip (SoC) includes first and second integrated processors or circuits respectively operating at first and second clock frequencies. The SoC includes a phase for detecting, for each frequency ratio between the first and second clock frequencies, a maximum rate of the data transfer, with the rate being a function of all the possible input and output delays supported by the SoC. This is dependent on the parameters of the SoC. There is also a phase for programming a generic frequency converter between the first and second integrated processors for the data transfer, and a phase for scheduling the data transfer between the semi-synchronous clock domains.