Invention Grant
- Patent Title: Charge tags and the separation of nucleic acid molecules
- Patent Title (中): 电荷标签和核酸分子的分离
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Application No.: US12132198Application Date: 2008-06-03
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Publication No.: US07678542B2Publication Date: 2010-03-16
- Inventor: Victor Lyamichev , Zbigniev Skrzypczynski , Hatim T. Allawi , Sarah R. Wayland , Tsetska Y. Takova , Bruce P. Neri , James R. Prudent , Jeff G. Hall
- Applicant: Victor Lyamichev , Zbigniev Skrzypczynski , Hatim T. Allawi , Sarah R. Wayland , Tsetska Y. Takova , Bruce P. Neri , James R. Prudent , Jeff G. Hall
- Applicant Address: US WI Madison
- Assignee: Third Wave Technologies, Inc.
- Current Assignee: Third Wave Technologies, Inc.
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones, S.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/00 ; C07H21/02
Abstract:
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including solid supports and nucleic acids, wherein the charge tags increase or decrease the net charge of the material. The present invention further provides methods for separating and characterizing molecules based on the charge differentials between modified and unmodified materials.
Public/Granted literature
- US20090078574A1 CHARGE TAGS AND THE SEPARATION OF NUCLEIC ACID MOLECULES Public/Granted day:2009-03-26
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