Invention Grant
US07678570B2 Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
失效
通过选择具有高细胞内蛋白质的菌株和用致癌物突变提供的用于蛋白质生产的人类细胞株
- Patent Title: Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
- Patent Title (中): 通过选择具有高细胞内蛋白质的菌株和用致癌物突变提供的用于蛋白质生产的人类细胞株
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Application No.: US10591521Application Date: 2004-10-27
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Publication No.: US07678570B2Publication Date: 2010-03-16
- Inventor: Hiroharu Kawahara
- Applicant: Hiroharu Kawahara
- Applicant Address: JP
- Assignee: Kitakyushu Foundation for the Advancement of Industry, Science and Technology
- Current Assignee: Kitakyushu Foundation for the Advancement of Industry, Science and Technology
- Current Assignee Address: JP
- Agency: Pepper Hamilton LLP
- Priority: JP2004-056551 20040301
- International Application: PCT/JP2004/016276 WO 20041027
- International Announcement: WO2005/083060 WO 20050909
- Main IPC: C12N5/08
- IPC: C12N5/08 ; C12N5/00
Abstract:
A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg per 1,000,000 cells; with the novel human cell strain being further characterized in that after a gene encoding a desired protein is transfected into it, the transfected cell is subsequently cultured.
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