Invention Grant
- Patent Title: Protein formulations for use at elevated temperatures
- Patent Title (中): 在高温下使用的蛋白质制剂
-
Application No.: US12145016Application Date: 2008-06-24
-
Publication No.: US07678764B2Publication Date: 2010-03-16
- Inventor: Venkata Garigapati , Dongling Su , Julius Lopez
- Applicant: Venkata Garigapati , Dongling Su , Julius Lopez
- Applicant Address: US MA Raynham
- Assignee: Johnson & Johnson Regenerative Therapeutics, LLC
- Current Assignee: Johnson & Johnson Regenerative Therapeutics, LLC
- Current Assignee Address: US MA Raynham
- Agent Stacey B. Antar
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/17 ; A61K38/18 ; A61K38/19 ; A61K31/195 ; A61K31/198 ; A61K31/205
Abstract:
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
Public/Granted literature
- US20090318343A1 Protein Formulations for Use at Elevated Temperatures Public/Granted day:2009-12-24
Information query
IPC分类:
