Invention Grant
US07678782B2 Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
失效
用于增强口服吸收和药物全身生物利用度的胆汁酸衍生化合物
- Patent Title: Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
- Patent Title (中): 用于增强口服吸收和药物全身生物利用度的胆汁酸衍生化合物
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Application No.: US11483770Application Date: 2006-07-11
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Publication No.: US07678782B2Publication Date: 2010-03-16
- Inventor: Mark A. Gallop , Kenneth C. Cundy
- Applicant: Mark A. Gallop , Kenneth C. Cundy
- Applicant Address: US CA Santa Clara
- Assignee: XenoPort, Inc.
- Current Assignee: XenoPort, Inc.
- Current Assignee Address: US CA Santa Clara
- Agent D. Byron Miller; William R. Lambert; Lucy S. Chang
- Main IPC: A61K31/56
- IPC: A61K31/56 ; C07J9/00
Abstract:
Disclosed are methods for providing enhanced systemic blood concentrations of orally delivered drugs that are incompletely translocated across the intestinal wall of an animal. Also disclosed are methods for the sustained release of drugs, whether poorly or readily bioavailable via oral delivery to animals. Still further, disclosed are compounds and pharmaceutical compositions that are used in such methods.
Public/Granted literature
- US20070015716A1 Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs Public/Granted day:2007-01-18
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