Invention Grant
- Patent Title: Pyrimidine derivatives for treatment of hyperproliferative disorders
- Patent Title (中): 嘧啶衍生物用于治疗过度增殖性疾病
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Application No.: US11078681Application Date: 2005-03-10
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Publication No.: US07678804B2Publication Date: 2010-03-16
- Inventor: Julie A. Dixon , Dhanapalan Nagarathnam , Lei Zhang , Chunguang Wang , Lin Yi , Yuanwei Chen , Jianqing Chen , Brian R. Bear , Michael Brands , Alexander Hillisch , Donald Bierer , Ming Wang , Wenlang Fu , Martin F. Hentemann , Ann-Marie Bullion , Manoj Patel
- Applicant: Julie A. Dixon , Dhanapalan Nagarathnam , Lei Zhang , Chunguang Wang , Lin Yi , Yuanwei Chen , Jianqing Chen , Brian R. Bear , Michael Brands , Alexander Hillisch , Donald Bierer , Ming Wang , Wenlang Fu , Martin F. Hentemann , Ann-Marie Bullion , Manoj Patel
- Applicant Address: US NY Tarrytown
- Assignee: Bayer Healthcare LLC
- Current Assignee: Bayer Healthcare LLC
- Current Assignee Address: US NY Tarrytown
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Nicholas J. DiCeglie, Jr.; Barry Kramer
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; C07D409/14 ; C07D413/14 ; A61K31/505 ; A61K31/506 ; A61P35/00
Abstract:
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
Public/Granted literature
- US07582646B2 Pyrimidine derivatives for treatment of hyperproliferative disorders Public/Granted day:2009-09-01
Information query
