Invention Grant
- Patent Title: Spiro-piperidine derivatives
- Patent Title (中): 螺哌啶衍生物
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Application No.: US11955434Application Date: 2007-12-13
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Publication No.: US07678806B2Publication Date: 2010-03-16
- Inventor: Caterina Bissantz , Christophe Grundschober , Raffaello Masciadri , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- Applicant: Caterina Bissantz , Christophe Grundschober , Raffaello Masciadri , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP06127078 20061222
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D471/10
Abstract:
The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases.In particular, the present invention is concerned with compounds of the general formula (I) wherein R1 to R5, R5′, X, Y and A are as defined in the specification.
Public/Granted literature
- US20080280898A1 Spiro-piperidine derivatives Public/Granted day:2008-11-13
Information query
