Invention Grant
US07678807B2 Isoquinoline and benzo[H] isoquinoline derivatives, preparation and therapeutic use thereof as antagonists of the histamine H3 receptor
有权
异喹啉和苯并[H]异喹啉衍生物,其作为组胺H3受体的拮抗剂的制备和治疗用途
- Patent Title: Isoquinoline and benzo[H] isoquinoline derivatives, preparation and therapeutic use thereof as antagonists of the histamine H3 receptor
- Patent Title (中): 异喹啉和苯并[H]异喹啉衍生物,其作为组胺H3受体的拮抗剂的制备和治疗用途
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Application No.: US12122795Application Date: 2008-05-19
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Publication No.: US07678807B2Publication Date: 2010-03-16
- Inventor: Juan Antonio Diaz Martin , Beatriz Escribano Arenales , Maria Dolores Jimenez Bargueno
- Applicant: Juan Antonio Diaz Martin , Beatriz Escribano Arenales , Maria Dolores Jimenez Bargueno
- Applicant Address: FR Paris
- Assignee: sanofi-aventis
- Current Assignee: sanofi-aventis
- Current Assignee Address: FR Paris
- Agent Balaram Gupta; Kelly L. Bender
- Priority: EP05111248 20051124
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D221/18 ; C07D221/22
![Isoquinoline and benzo[H] isoquinoline derivatives, preparation and therapeutic use thereof as antagonists of the histamine H3 receptor](/abs-image/US/2010/03/16/US07678807B2/abs.jpg.150x150.jpg)
Abstract:
The invention concerns a compound of formula (I): Wherein A, l, m, n, R1 and R2 are as defined herein. The compounds of this invention are useful as medicaments, particularly, in the treatment of disorders improved by modulation of the histamine H3 receptor.
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