Invention Grant
US07678811B2 Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
有权
吡啶，喹啉和异喹啉N-氧化物作为激酶抑制剂
- Patent Title: Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
- Patent Title (中): 吡啶，喹啉和异喹啉N-氧化物作为激酶抑制剂
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Application No.: US11775457Application Date: 2007-07-10
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Publication No.: US07678811B2Publication Date: 2010-03-16
- Inventor: Jacques Dumas , William J. Scott , Bernd Riedl
- Applicant: Jacques Dumas , William J. Scott , Bernd Riedl
- Applicant Address: US NY Tarrytown
- Assignee: Bayer Healthcare LLC
- Current Assignee: Bayer Healthcare LLC
- Current Assignee Address: US NY Tarrytown
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: C07D401/02
- IPC: C07D401/02 ; A61K31/44 ; A61K31/47
Abstract:
This invention relates to urea compounds containing a pyridine, quinoline, or isoquinoline functionality which is oxidized at the nitrogen heteroatom and which are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angogenesis disorders.
Public/Granted literature
- US20070265315A1 PYRIDINE, QUINOLINE, AND ISOQUINOLINE N-OXIDES AS KINASE INHIBITORS Public/Granted day:2007-11-15
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