Invention Grant
US07678812B2 Aminotetralin-derived urea modulators of vanilloid VR1 receptor
有权
氨基四氢萘衍生的脲类VR1受体的尿素调节剂
- Patent Title: Aminotetralin-derived urea modulators of vanilloid VR1 receptor
- Patent Title (中): 氨基四氢萘衍生的脲类VR1受体的尿素调节剂
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Application No.: US11877220Application Date: 2007-10-23
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Publication No.: US07678812B2Publication Date: 2010-03-16
- Inventor: Ellen Codd , Scott L. Dax , Michele Jetter , Mark McDonnell , James J. McNally , Mark Youngman
- Applicant: Ellen Codd , Scott L. Dax , Michele Jetter , Mark McDonnell , James J. McNally , Mark Youngman
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D211/06 ; C07D217/22
Abstract:
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
Public/Granted literature
- US20080097102A1 AMINOTETRALIN-DERIVED UREA MODULATORS OF VANILLOID VR1 RECEPTOR Public/Granted day:2008-04-24
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