Invention Grant
US07678819B2 Acetylene derivatives and their use for binding and imaging amyloid plaques
失效
乙炔衍生物及其用于结合和成像淀粉样斑块的用途
- Patent Title: Acetylene derivatives and their use for binding and imaging amyloid plaques
- Patent Title (中): 乙炔衍生物及其用于结合和成像淀粉样斑块的用途
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Application No.: US11951612Application Date: 2007-12-06
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Publication No.: US07678819B2Publication Date: 2010-03-16
- Inventor: Hank F. Kung , Mei Ping Kung
- Applicant: Hank F. Kung , Mei Ping Kung
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Woodcock Washburn LLP
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/24 ; C07D213/56
Abstract:
The invention relates to radiolabeled compounds and their use in methods of imaging amyloid deposits, as well as to methods of their manufacture. The invention also relates to compounds for inhibiting the aggregation of amyloid proteins that form amyloid deposits, methods for delivering therapeutic agents to amyloid deposits, as well as methods of making compounds that inhibit the aggregation of amyloid proteins.
Public/Granted literature
- US20080166299A1 Acetylene Derivatives And Their Use For Binding And Imaging Amyloid Plaques Public/Granted day:2008-07-10
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