Invention Grant
US07678888B2 Stable oxidation resistant powdered hemoglobin, methods of preparing same, and uses thereof
失效
稳定的抗氧化粉末血红蛋白，其制备方法及其用途
- Patent Title: Stable oxidation resistant powdered hemoglobin, methods of preparing same, and uses thereof
- Patent Title (中): 稳定的抗氧化粉末血红蛋白，其制备方法及其用途
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Application No.: US10593387Application Date: 2005-04-20
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Publication No.: US07678888B2Publication Date: 2010-03-16
- Inventor: Joel M. Friedman , Mahantesh S. Navati
- Applicant: Joel M. Friedman , Mahantesh S. Navati
- Applicant Address: US NY Bronx
- Assignee: Albert Einstein College of Medicine of Yeshiva University
- Current Assignee: Albert Einstein College of Medicine of Yeshiva University
- Current Assignee Address: US NY Bronx
- Agency: Amster, Rothstein & Ebenstein LLP
- International Application: PCT/US2005/013222 WO 20050420
- International Announcement: WO2005/103080 WO 20051103
- Main IPC: C07K14/00
- IPC: C07K14/00
Abstract:
The present invention provides oxygenated hemoglobins in powdered form and methods of preparing a powdered form of a protein, such as hemoglobin, which comprise (a) mixing a solution of the protein with inulin, and optimally with a reducing sugar such as glucose or tagatose, and (b) drying the mixture. Also provided are blood substitutes formed from reconstituted powdered hemoglobins, and methods of treatment using the blood substitutes.
Public/Granted literature
- US20080039370A1 Stable Oxidation Resistant Powdered Hemoglobin, Methods of Preparing Same, and Uses Thereof Public/Granted day:2008-02-14
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