Invention Grant
US07678896B2 siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)
有权
靶向丝氨酸/苏氨酸激酶12的siRNA（STK12或极光B激酶）
- Patent Title: siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)
- Patent Title (中): 靶向丝氨酸/苏氨酸激酶12的siRNA（STK12或极光B激酶）
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Application No.: US11818938Application Date: 2007-06-15
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Publication No.: US07678896B2Publication Date: 2010-03-16
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to STK12.
Public/Granted literature
- US20070276136A1 siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase) Public/Granted day:2007-11-29
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