Invention Grant
- Patent Title: Ureas as factor Xa inhibitors
- Patent Title (中): 尿素作为因子Xa抑制剂
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Application No.: US11298317Application Date: 2005-12-07
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Publication No.: US07678913B2Publication Date: 2010-03-16
- Inventor: Yonghong Song , Bing-Yan Zhu , Shumei Wang , Chhaya Bhakta , Robert M. Scarborough
- Applicant: Yonghong Song , Bing-Yan Zhu , Shumei Wang , Chhaya Bhakta , Robert M. Scarborough
- Applicant Address: US CA South San Francisco
- Assignee: Portola Pharmaceuticals, Inc.
- Current Assignee: Portola Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: A61K31/48
- IPC: A61K31/48 ; C07D207/40 ; C07D215/38
Abstract:
The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
Public/Granted literature
- US20060160821A1 Ureas as factor Xa inhibitors Public/Granted day:2006-07-20
Information query
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