The present invention is a driving circuit applied to a piezoelectric activation element, which comprises: a driving period generation unit and a switch circuit unit. The driving period generation unit further comprises: a driving indication signal and a programmable micro-controller, in which the programmable micro-controller is to receive the driving indication signal, and to generate a programmable driving period signal in response to the driving indication signal; and, the switch circuit unit is connected to the driving period generation unit and the piezoelectric activation element, and to receive the driving period signal, and generate an alternate driving voltage in response to the driving period signal; in which, the half-wave leading edge of the alternate driving voltage has the waveform of a parabolic curve waveform, and the half-wave trailing edge of the alternate driving voltage has the waveform of approximately a vertical line waveform, and the alternate driving voltage is connected to the piezoelectric activation element.