Aspects of a method and system for a highly efficient power amplifier (PA) utilizing dynamic biasing and predistortion are presented. Aspects of the system may include a processor that enables computation of a value of a variable bias component of a bias current based on a bias slope value and an amplitude of an envelope input signal. The processor may enable computation of a value of the bias current based on the selected constant bias current component value and the variable bias current component value. A PA may enable generation of an output signal in response to a generated baseband signal by utilizing the bias current to amplify an amplifier input signal. The bias current may be generated based on the envelope input signal. A feedback signal may be generated based on the output signal, which may be used to predistort a subsequent baseband signal.