A liquid crystal display panel includes a color filter, a thin film transistor substrate in opposition to the color filter, a liquid crystal layer provided between the color filter and the thin film transistor substrate and a sealant provided corresponding to the mark regions and surrounding the liquid crystal layer. The mark regions are provided on periphery of the thin film transistor substrate and each includes a plurality of alignment marks as references for applying the frame sealant and therefore controlling the applying amount and rate of the frame sealant so that the applied frame sealant has line width of desired specification and that the distance between the substrates is desirably determined. A related method for manufacturing a liquid crystal display panel is also provided.