A Real-Time Protocol (RTP) source node of a network operates to send a first data packet of a first size to a destination node over a path of the network that includes a plurality of intermediate nodes, at least one of the intermediate nodes having a maximum transmission unit (MTU) size smaller than the first size such that fragmentation of the first data packet occurs. The destination node sends back to the source node a RTCP report that includes a number of fragments received and a largest minimum data packet size. In response, the source node sends subsequent data packets having a second size less than or equal to the largest data packet size of the fragments. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.