An apparatus for making and administering two non-homogenous liquids to target tissue includes a spray comprising two syringes for containing the first and second non-homogenous liquid where the syringes are adapted to be removably coupled to an applicator. The applicator includes a pair of elongated tubes each having a tubular sheath at a proximal end, a distal end and a lumen in which the pair of elongated tubes are disposed. The apparatus includes a regulator module having an inlet port adapted for connection to a source of gas under pressure and a gas outlet port adopted for connection to the gas inlet port of the sheet. A vent gas inlet port is adapted for connection to a vent port of an endoscopic cannula where the regulator vents a quantity of gas from the endoscopic cannula approximately equal to a quantity of gas introduced at the gas inlet port of the sheet.