Invention Grant
US07682351B2 Method for infusing insulin to a subject to improve impaired hepatic glucose processing 有权
将胰岛素注射到受试者以改善肝葡萄糖加工受损的方法

  • Patent Title: Method for infusing insulin to a subject to improve impaired hepatic glucose processing
  • Patent Title (中): 将胰岛素注射到受试者以改善肝葡萄糖加工受损的方法
  • Application No.: US10738897
    Application Date: 2003-12-17
  • Publication No.: US07682351B2
    Publication Date: 2010-03-23
  • Inventor: Thomas T. Aoki
  • Applicant: Thomas T. Aoki
  • Agent Eric G. Masamori
  • Main IPC: A61M31/00
  • IPC: A61M31/00
Method for infusing insulin to a subject to improve impaired hepatic glucose processing
Abstract:
The present invention is a method for delivering insulin to a subject to improve impaired hepatic glucose processing. The method delivers a series of pulses of insulin to the subject over a period of time accompanied by ingestion of glucose in the form of a carbohydrate containing meal. The amount of insulin in each pulse, the interval between pulses and the amount of time to deliver each pulse to the subject are selected so that the hepatic processing of glucose is restored in the subject. In subjects whose hepatic glucose processing has been restored there is a subsequent fall in circulating blood glucose levels of 50 mg/dl or more directly as a result of improved hepatic glucose processing.
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