Invention Grant
- Patent Title: Generation of virus-like particles and use as panfilovirus vaccine
- Patent Title (中): 生成病毒样颗粒并用作泛病毒疫苗
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Application No.: US11105031Application Date: 2005-04-13
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Publication No.: US07682618B2Publication Date: 2010-03-23
- Inventor: Sina Bavari , M. Javad Aman , Alan L. Schmaljohn , Kelly L. Warfield , Dana Swenson
- Applicant: Sina Bavari , M. Javad Aman , Alan L. Schmaljohn , Kelly L. Warfield , Dana Swenson
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Elizabeth Arwine
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12Q1/70 ; C12N7/00 ; C12N5/10
Abstract:
In this application are described filovirus-like particles for both Ebola and Marburg and their use as a diagnostic and therapeutic agent as well as a filovirus vaccine. Also described is the association of Ebola and Marburg with lipid rafts during assembly and budding, and the requirement of functional rafts for entry of filoviruses into cells.
Public/Granted literature
- US20050266023A1 Generation of virus-like particles and use as panfilovirus vaccine Public/Granted day:2005-12-01
Information query
