Invention Grant
- Patent Title: Triazine dimers for the treatment of autoimmune diseases
- Patent Title (中): 三嗪二聚体治疗自身免疫性疾病
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Application No.: US10580237Application Date: 2004-11-22
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Publication No.: US07683061B2Publication Date: 2010-03-23
- Inventor: Christopher Penney , Boulos Zacharie , Shaun D. Abbott , Jean-François Bienvenu , Alan D. Cameron , Jean-Simon Duceppe , Abdallah Ezzitouni , Daniel Fortin , Karine Houde , Nancie Moreau , Nicole Wilb , Brigitte Grouix , Lyne Gagnon
- Applicant: Christopher Penney , Boulos Zacharie , Shaun D. Abbott , Jean-François Bienvenu , Alan D. Cameron , Jean-Simon Duceppe , Abdallah Ezzitouni , Daniel Fortin , Karine Houde , Nancie Moreau , Nicole Wilb , Brigitte Grouix , Lyne Gagnon
- Applicant Address: CA Montreal, Quebec
- Assignee: ProMetic BioSciences Inc.
- Current Assignee: ProMetic BioSciences Inc.
- Current Assignee Address: CA Montreal, Quebec
- Agency: Clark & Elbing LLP
- International Application: PCT/CA2004/002003 WO 20041122
- International Announcement: WO2005/049607 WO 20050602
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D403/14 ; A61K31/53 ; A61K39/395 ; A61P13/12 ; A61P17/06 ; A61P19/02 ; A61P37/00 ; A61M1/36 ; C07K1/22 ; C07K16/24

Abstract:
Compounds containing two mono- or disubstituted triazine rings covalently linked by an organic linker, but not linked directly to each other, may be used to treat autoimmune diseases. Autoimmune diseases which are amenable to treatment with compounds of this invention include rheumatoid arthritis, systemic lupus erythematosus (SLE), idiopathic (immune) thrombocytopenia (ITP), glomerulonephritis and vasculitis. The present invention also relates to reducing drug toxicity which often accompanies traditional therapies for autoimmune diseases. The compounds may also be used to bind antibody in vitro or ex vivo.
Public/Granted literature
- US20070149528A1 Triazine dimers for the treatment of autoimmune diseases Public/Granted day:2007-06-28
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