Invention Grant
US07683071B2 Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
失效
用于提高5,5-二苯基巴比妥酸的生物利用度和增强脑输送的组合物和方法
- Patent Title: Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
- Patent Title (中): 用于提高5,5-二苯基巴比妥酸的生物利用度和增强脑输送的组合物和方法
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Application No.: US11201024Application Date: 2005-08-10
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Publication No.: US07683071B2Publication Date: 2010-03-23
- Inventor: Daniella Gutman , Barrie Levitt , Daniel Moros , Avraham Yacobi , Howard Rutman
- Applicant: Daniella Gutman , Barrie Levitt , Daniel Moros , Avraham Yacobi , Howard Rutman
- Applicant Address: IL Haifa Bay
- Assignee: Taro Pharmaceuticals Industries Ltd.
- Current Assignee: Taro Pharmaceuticals Industries Ltd.
- Current Assignee Address: IL Haifa Bay
- Agency: Venable LLP
- Agent Michael A. Gollin; Keith G. Haddaway
- Main IPC: A61K31/515
- IPC: A61K31/515 ; C07D239/62 ; C07D239/64
Abstract:
The present invention relates to a composition and a method of delivering a barbituric acid derivative to the central nervous system of a mammal in need of treatment for neurological conditions. In particular, the present invention relates to a method of administering an oral dosage form of a sodium salt of 5,5-diphenyl barbituric acid to enhance the bioavailability of 5,5-diphenyl barbituric acid and brain delivery of same.
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