Invention Grant
US07683082B2 1,2,4-oxadiazole benzoic acid compositions and their use in bioassays
失效
1,2,4-恶二唑苯甲酸组合物及其在生物测定中的应用
- Patent Title: 1,2,4-oxadiazole benzoic acid compositions and their use in bioassays
- Patent Title (中): 1,2,4-恶二唑苯甲酸组合物及其在生物测定中的应用
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Application No.: US11724408Application Date: 2007-03-14
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Publication No.: US07683082B2Publication Date: 2010-03-23
- Inventor: Gary Mitchell Karp , Seongwoo Hwang , Guangming Chen , Neil Gregory Almstead , Young-Choon Moon
- Applicant: Gary Mitchell Karp , Seongwoo Hwang , Guangming Chen , Neil Gregory Almstead , Young-Choon Moon
- Applicant Address: US NJ South Plainfield
- Assignee: PTC Therapeutics, Inc.
- Current Assignee: PTC Therapeutics, Inc.
- Current Assignee Address: US NJ South Plainfield
- Agency: Jones Day
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D271/06

Abstract:
Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
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