Invention Grant
- Patent Title: Topoisomerase inhibitors
- Patent Title (中): 拓扑异构酶抑制剂
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Application No.: US11138636Application Date: 2005-05-25
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Publication No.: US07683097B2Publication Date: 2010-03-23
- Inventor: Martin A. Murphy , John Robert Schullek , John S. Ward , Gary C. Look , Brian Siesel
- Applicant: Martin A. Murphy , John Robert Schullek , John S. Ward , Gary C. Look , Brian Siesel
- Applicant Address: US CA San Jose
- Assignee: Propharmacon Inc.
- Current Assignee: Propharmacon Inc.
- Current Assignee Address: US CA San Jose
- Main IPC: C07C233/64
- IPC: C07C233/64 ; C07D251/12 ; C07D241/10 ; C07D239/24 ; C07D207/04 ; C07D213/02 ; C07D277/08 ; C07D307/04 ; A61K31/53 ; A61K31/505 ; A61K31/166 ; A61K31/34 ; A61K31/40 ; A61K31/44 ; A61K31/445 ; A61K31/4965 ; A61P35/00

Abstract:
The present invention provides compounds that are effective against inhibiting topoisomerase (i.e., topoisomerase I and/or topoisomerase II). These compounds are used for treating cell-proliferative disorders. In some instances, these compounds have anticancer activity, e.g., against multi-drug resistant cancers.
Public/Granted literature
- US20070004701A1 Topoisomerase inhibitors Public/Granted day:2007-01-04
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