Invention Grant
- Patent Title: Method for the synthesis of a benzimidazole compound
- Patent Title (中): 苯并咪唑化合物的合成方法
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Application No.: US11749282Application Date: 2007-05-16
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Publication No.: US07683178B2Publication Date: 2010-03-23
- Inventor: Anders Gustavsson
- Applicant: Anders Gustavsson
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: White & Case LLP
- Priority: SE0203092 20021018
- Main IPC: C07D401/12
- IPC: C07D401/12
Abstract:
A process for the manufacture of omeprazole or esomeprazole from pyrmethyl alcohol via pyrmethyl chloride and pyrmetazole characterized in that the whole reaction sequence is carried out without any isolation or purification of intermediates. Further, the reaction is carried out in a solvent system common for the whole reaction sequence and inert to the reactants formed during the process and used in the process and comprises a water immiscible organic solvent and a specified amount of water.
Public/Granted literature
- US20080004447A1 Method for the Synthesis of a Benzimidazole Compound Public/Granted day:2008-01-03
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