A system, pharmacy management software, and related methods of enhanced pharmaceutical operations in patient care facilities are provided. The pharmacy management software, for example, can include instructions that when executed by a computer, cause the computer to perform the operations of providing instructions to pharmaceutical storage and electronic dispensing carts positioned at various patient care facilities according to patient specific prescription requirements, receiving dispensing data from each of the carts, and providing separate billing records including billing data indexed by reimbursement provider for each patient at the patient care facilities. The operations can also include consolidating the billing data by patient, by patient care facility, by remote pharmacy, and/or consolidating billing data by reimbursement provider, and submitting separate consolidated reimbursement claims electronically to each respective reimbursement provider.