An exhaust system for a saddle-ride type vehicle provides sufficient volume in a chamber while avoiding interference between the chamber and other parts. The vehicle center of gravity is lowered and differences in exhaust pipe length are reduced. Exhaust pipes are connected to combustion chambers of front and rear cylinder banks of a V-type engine. A chamber is connected to the exhaust pipes and mufflers are connected to the chamber. The chamber has an exhaust pipe connection wall to which the exhaust pipes are connected and opposing muffler connection walls. The mufflers are connected to positions on the muffler connection walls closer to the engine relative to a center in a longitudinal direction of the vehicle.