A system for mitigating pain in a patient associated with needle penetration in the administration of medication, and in particular to a vibratory device configured to be utilized with a variety of existing hand-held intra-oral dental drills or like devices. The preferred embodiment of the present invention teaches a disposable or non-disposable vibratory tip formed to engage an off-the-shelf intra-oral dental drill, the vibratory tip utilizing an off-axis weight associated with a shaft drive engaging the dental drill, to provide a vibratory sensation to an application tip, the application tip configured to engage an area of a patient's mouth targeted for the subsequent needled administration of local anesthetic, or other medication. In use, the application tip is applied to the patient, the dental drill is engaged to rotate the shaft drive of the vibratory tip, vibrating same for period of time, so as to decrease the sensation of pain associated with the subsequent needle penetration.