Invention Grant
- Patent Title: Method of identification and quantification of proteins, isoforms of the angiotensin I converting enzyme
- Patent Title (中): 鉴定和定量蛋白质的方法，血管紧张素I转化酶的同种型
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Application No.: US10540193Application Date: 2003-12-22
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Publication No.: US07687237B2Publication Date: 2010-03-30
- Inventor: Dulce Elena Casarini , Odair Marson , Frida Liane Plavnik , José Eduardo Krieger
- Applicant: Dulce Elena Casarini , Odair Marson , Frida Liane Plavnik , José Eduardo Krieger
- Applicant Address: BR Sao Paulo
- Assignee: Universidade Federal de Sao Paulo - UNIFESP
- Current Assignee: Universidade Federal de Sao Paulo - UNIFESP
- Current Assignee Address: BR Sao Paulo
- Agency: Ohlandt, Greeley, Ruggiero & Perle, LLP
- Priority: BR0206903 20021220
- International Application: PCT/BR03/00202 WO 20031222
- International Announcement: WO2004/057020 WO 20040708
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present invention relates to a method of identification and quantification of proteins, isoforms of angiotensin I converting enzymes (ACE), 190-kDa, specially of 90kDa in tissues, cells and biological fluids, specially in urine, genetic marker and prognostic agent of hypertension and primary or secondary renal lesion and kit for using in the diagnosis, risk stratification and therapeutical decision in arterial hypertension. One the aims of the present invention is to check the potential of the 90 kDa isoform as a hypertension genetic marker isoform and as a prognostic for hypertension.
Public/Granted literature
- US20060057739A1 Method of identification and quantification of proteins, isoforms of the angiotensin i converting enzyme Public/Granted day:2006-03-16
Information query
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