Invention Grant
US07687461B2 Treatment of TNF-α related disorders with TNF-α variant proteins
有权
用TNF-α变体蛋白处理TNF-α相关病症
- Patent Title: Treatment of TNF-α related disorders with TNF-α variant proteins
- Patent Title (中): 用TNF-α变体蛋白处理TNF-α相关病症
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Application No.: US10963994Application Date: 2004-10-12
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Publication No.: US07687461B2Publication Date: 2010-03-30
- Inventor: John R. Desjarlais , Anton Filikov , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski
- Applicant: John R. Desjarlais , Anton Filikov , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan Lewis & Bockius LLP
- Agent Robin M. Silva, Esq.; David C. Foster, Esq.
- Main IPC: A61K38/19
- IPC: A61K38/19 ; C07K14/525
Abstract:
The invention relates to novel proteins with TNF-alpha antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-alpha related disorders.
Public/Granted literature
- US20050180948A1 Protein based TNF-alpha variants for the treatment of TNF-alpha related disorders Public/Granted day:2005-08-18
Information query
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