Invention Grant
- Patent Title: Genetic vaccines directed against bacterial exotoxins
- Patent Title (中): 针对细菌外毒素的遗传疫苗
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Application No.: US10649457Application Date: 2003-08-27
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Publication No.: US07687613B2Publication Date: 2010-03-30
- Inventor: Ronald G. Crystal , Neil R. Hackett , Yadi Tan
- Applicant: Ronald G. Crystal , Neil R. Hackett , Yadi Tan
- Applicant Address: US NY Ithaca
- Assignee: Cornell Research Foundation, Inc.
- Current Assignee: Cornell Research Foundation, Inc.
- Current Assignee Address: US NY Ithaca
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00
Abstract:
The invention provides a gene transfer vector comprising a humanized nucleic acid sequence encoding an immunogenic portion of one or more exotoxins of Bacillus anthracis and a heterologous sorting signal. The invention also provides a method of producing an immune response against Bacillus anthracis in a host comprising administering to the host the gene transfer vector.
Public/Granted literature
- US20060019380A1 Genetic vaccines directed against bacterial exotoxins Public/Granted day:2006-01-26
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