Invention Grant
- Patent Title: 2-methylprop anamides and their use as pharmaceuticals
- Patent Title (中): 2-甲基丙酰胺及其作为药物的用途
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Application No.: US11159865Application Date: 2005-06-23
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Publication No.: US07687665B2Publication Date: 2010-03-30
- Inventor: Wenqing Yao , Colin Zhang , Jincong Zhuo , Meizhong Xu , Konstantinos Agrios , Brian Metcalf
- Applicant: Wenqing Yao , Colin Zhang , Jincong Zhuo , Meizhong Xu , Konstantinos Agrios , Brian Metcalf
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07C233/05
- IPC: C07C233/05 ; A61K31/165

Abstract:
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Public/Granted literature
- US20050288329A1 2-Methylprop anamides and their use as pharmaceuticals Public/Granted day:2005-12-29
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