Invention Grant
US07691297B2 Process for the manufacture of powderous preparations of fat-soluble substances 有权
制造脂溶性物质粉末制剂的方法

  • Patent Title: Process for the manufacture of powderous preparations of fat-soluble substances
  • Patent Title (中): 制造脂溶性物质粉末制剂的方法
  • Application No.: US10541359
    Application Date: 2004-01-06
  • Publication No.: US07691297B2
    Publication Date: 2010-04-06
  • Inventor: David Schaffner
  • Applicant: David Schaffner
  • Applicant Address: NL Heerlen
  • Assignee: DSM IP Assets B.V.
  • Current Assignee: DSM IP Assets B.V.
  • Current Assignee Address: NL Heerlen
  • Agency: Nixon & Vanderhye P.C.
  • Priority: EP03000365 20030110
  • International Application: PCT/EP2004/000028 WO 20040106
  • International Announcement: WO2004/062382 WO 20040729
  • Main IPC: A61K9/14
  • IPC: A61K9/14 A61K31/12 A61K31/015
Process for the manufacture of powderous preparations of fat-soluble substances
Abstract:
In a process for the manufacture of beadlet preparations of fat-soluble substances in a water-soluble or water-dispersible non-gelling matrix, an aqueous emulsion of the fat-soluble substance(s) and the matrix component are fed through a spray nozzle in the upper section of a vertical spray tower. Through separate inlets powderous starch and a stream of hot air are also fed in the upper section of the vertical spray tower. A stream of cold air is fed in the lower section of the spray tower so as to form a fluidised bed of starch-covered beadlets comprising the matrix component as well as the fat-soluble substances. The beadlets are collected from the fluidised bed and are discharged to a dryer.
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