Invention Grant
US07691376B2 Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof
失效
卵巢癌细胞和骨髓瘤细胞表面糖蛋白，其抗体及其用途
- Patent Title: Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof
- Patent Title (中): 卵巢癌细胞和骨髓瘤细胞表面糖蛋白，其抗体及其用途
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Application No.: US11753221Application Date: 2007-05-24
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Publication No.: US07691376B2Publication Date: 2010-04-06
- Inventor: Cohava Gelber
- Applicant: Cohava Gelber
- Applicant Address: US CA Woodland Hills
- Assignee: ImmunoCellular Therapeutics, Ltd.
- Current Assignee: ImmunoCellular Therapeutics, Ltd.
- Current Assignee Address: US CA Woodland Hills
- Agency: Locke Lord Bissell & Liddell, LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention is directed to cell surface antigens found on myeloma cells and on ovarian cancer cells that are recognized by monoclonal antibodies, and antibody binding fragments thereof, as described. The monoclonal antibodies of the invention are capable of being used for therapeutic, screening, diagnostic and cell purification purposes. A representative and exemplified monoclonal antibody of the present invention recognizes and binds to an epitope common to a surface antigen that is expressed on multiple myeloma cells and to a surface antigen that is expressed on ovarian cancer cells. The function of this monoclonal antibody both in vivo and in vitro is demonstrated.
Public/Granted literature
- US20070269372A1 OVARIAN CANCER CELL AND MYELOMA CELL SURFACE GLYCOPROTEINS, ANTIBODIES THERETO, AND USES THEREOF Public/Granted day:2007-11-22
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